SS-31
What is SS-31?
SS-31, also known as Elamipretide, is a synthetic peptide designed to target and protect mitochondria, the powerhouses of cells. It is often researched for its potential to improve cellular energy production, reduce oxidative stress, and support conditions involving mitochondrial dysfunction, such as heart failure, neurodegenerative diseases, and aging.
How It Works (Mechanism of Action)
SS-31 penetrates cell membranes and accumulates in the inner mitochondrial membrane, where it binds to cardiolipin, a key lipid. This stabilizes mitochondrial function, reduces reactive oxygen species (ROS), and enhances ATP production, improving cellular energy and resilience.
Potential Benefits & Use Cases
- Mitochondrial Health: Protects mitochondria from damage and improves energy production.
- Anti-Aging: Reduces oxidative stress, supporting cellular longevity.
- Cardiovascular Support: May improve heart function in conditions like heart failure.
- Neuroprotection: Supports brain health in neurodegenerative diseases.
- Exercise Performance: Enhances endurance by improving mitochondrial efficiency.
Typical Dosage & Administration
Administration: Subcutaneous injection.
Dosage:
- Typical doses range from 5 mg to 10 mg per injection.
- Often administered 2-3 times per week.
Possible Side Effects
- Injection Site Reactions: Mild redness or irritation at the injection site.
- Fatigue: Temporary tiredness in some users.
- Unknown Long-Term Effects: Still under investigation for long-term safety.
Other Relevant Details
- Under investigation for mitochondrial diseases, heart failure, and neurodegenerative disorders.
- May be stacked with other mitochondrial peptides like MOTS-c for enhanced effects.