Retatrutide
What is Retatrutide?
Retatrutide is a synthetic peptide and a triple agonist of GLP-1, GIP, and glucagon receptors, designed for weight loss and metabolic health. It is researched for its ability to reduce appetite, improve glucose control, and promote significant fat loss.
How It Works (Mechanism of Action)
Retatrutide activates GLP-1, GIP, and glucagon receptors, leading to reduced appetite, increased satiety, enhanced insulin secretion, and improved fat metabolism. This triple action makes it highly effective for weight loss and metabolic regulation.
Potential Benefits & Use Cases
- Weight Loss: Promotes significant fat loss and appetite suppression.
- Metabolic Health: Improves insulin sensitivity and glucose control.
- Obesity Research: Studied for its triple action in obesity management.
Typical Dosage & Administration
Administration: Subcutaneous injection.
Dosage:
- Typical doses range from 1 mg to 5 mg per week.
- Often administered once weekly, with gradual dose escalation.
Possible Side Effects
- Nausea: Common during initial use, typically subsides.
- Injection Site Reactions: Mild redness or irritation.
- Gastrointestinal Discomfort: Possible bloating or diarrhea.
Other Relevant Details
- Under investigation for long-term efficacy in obesity and diabetes treatment.
- May offer superior weight loss results compared to single-receptor agonists.