Vilon 20mg
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Vilon 20mg: A synthetic dipeptide designed to support immune function and promote anti-aging effects. Vilon enhances immune system activity by stimulating immune cell production and regulating immune responses, while also supporting cellular repair and regeneration, which may contribute to improved tissue health and longevity. It is used to boost immunity and aid in recovery from age-related decline or immune stress.
Vilon 20mg
What is Vilon?
Vilon 20mg is a synthetic dipeptide, also known as lysylglutamic acid (Lys-Glu), composed of lysine and glutamic acid. It is a potent bioregulator peptide researched for its immunomodulatory, anti-aging, and tissue regeneration properties. Vilon primarily interacts with the thymus to enhance T-cell development and immune function, showing promise in combating age-related decline, infections, and certain cancers.
[](https://www.peptidesciences.com/vilon-20mg)[](https://www.corepeptides.com/vilon-peptide-research-into-immune-cell-proliferation-differentiation-and-regulation/)
How It Works (Mechanism of Action)
Vilon modulates gene expression and chromatin structure to promote immune and cellular function:
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- Chromatin Regulation: Induces unrolling of chromatin (euchromatin formation) without decondensing pericentromeric heterochromatin, reactivating silenced genes to enhance protein synthesis and cellular activity.
[](https://www.peptidesciences.com/vilon-20mg)
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- Immune Activation: Stimulates thymocyte proliferation and differentiation, increasing CD5 and CD4+ T-helper cell expression, boosting T-cell maturation, and enhancing interleukin-2 (IL-2) signaling in splenocytes for immune coordination.
[](https://www.corepeptides.com/vilon-peptide-research-into-immune-cell-proliferation-differentiation-and-regulation/)[](https://biotechpeptides.com/product/vilon-20mg/)
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- Anti-Inflammatory Effects: Reduces autoimmune reactions by regulating T-helper and cytotoxic CD8+ T-cell activity, preventing excessive immune responses.
[](https://www.peptidesciences.com/vilon-20mg)
- Tissue Regeneration: Promotes reparative processes in organs like the liver and intestines post-irradiation or injury by stimulating stem cell activity and protein synthesis.[](https://e-peptide.com/shop-information/peptide-therapy/vilon-20mg-peptide-immunomodulator-with-tissue-regeneration-and-healing-action-detail)
These actions enhance immune resilience, support tissue repair, and mitigate age-related cellular senescence.
Potential Benefits & Use Cases
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- Immune Enhancement: Boosts T-cell and splenocyte activity, improving resistance to infections (e.g., viral, bacterial) and supporting recovery in immunocompromised models.
[](https://biotechpeptides.com/product/vilon-20mg/)
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- Anti-Aging Effects: Extends lifespan in mice by increasing physical endurance and reducing age-related thymic involution, with early administration yielding greater geroprotective effects.
[](https://molchanges.com/product/vilon)
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- Cancer Prevention: Reduces incidence and growth of spontaneous tumors in murine models, potentially acting as a chemotherapeutic agent, though its role in cancer treatment is debated.
[](https://www.peptidesciences.com/vilon-20mg)[](https://biotechpeptides.com/product/vilon-20mg/)
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- Tissue Regeneration: Accelerates healing of liver, intestinal, and thymic tissues post-injury or irradiation; enhances collagen and elastin synthesis for skin and connective tissue repair.
[](https://e-peptide.com/shop-information/peptide-therapy/vilon-20mg-peptide-immunomodulator-with-tissue-regeneration-and-healing-action-detail)[](https://nanopep.net/products/pan-vilon/)
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- Gastrointestinal Health: Improves enzyme activity, barrier function, and glucose/glycine absorption in the small intestine, potentially reducing leaky gut and enhancing nutrient uptake.
[](https://biotechpeptides.com/2022/07/29/vilon-peptide-and-cell-aging/)
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- Cardiovascular and Renal Support: May modulate gene expression in the heart (up to 36 genes) and reduce kidney microvessel permeability, improving coagulation and fibrinolysis in diabetic models.
[](https://biotechpeptides.com/2022/07/29/vilon-peptide-and-cell-aging/)
Typical Dosage & Administration
Administration: Subcutaneous injection, typically administered daily or 2-3 times weekly, depending on the research protocol.
Reconstitution: A 20mg vial is typically reconstituted with 1-2 ml bacteriostatic water, yielding 10-20 mg/ml (e.g., 5 mg = 0.25-0.5 ml). Use aseptic technique, gently swirl to mix, and avoid shaking to preserve peptide integrity.
Dosage:
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- Standard Research Dose: 5 mg daily for a 10-12 day cycle, repeated every 4-6 months, requiring ~3 vials of 20mg for a full cycle.
[](https://world-of-peptides.com/vilon-a-comprehensive-peptide-guide-to-its-uses-benefits-dosage-and-in-depth-insights/)
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- Alternative Protocols: 0.1-1 mg/kg daily or 1-10 µg/kg in murine models, adjusted for body weight; lower doses (e.g., 50 nM) used in cell culture studies.
[](https://www.peptides.org/vilon-dosage-calculator/)[](https://www.researchgate.net/publication/225521540_The_effects_of_vilon_and_epithalon_peptides_on_the_expression_of_neprilysin_and_insulin-degrading_enzyme_in_human_neuroblastoma_NB7_cells_under_normal_and_hypoxic_conditions)
- Protocol Example: A 20mg vial supports ~4 doses at 5 mg or ~40 doses at 0.5 mg. Administer early in life for optimal anti-aging effects; consult a professional for precise regimens.
Possible Side Effects
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- Injection Site Reactions: Mild redness or irritation at the injection site, typically resolving quickly.
- Digestive Upset: Rare reports of mild gastrointestinal discomfort in some subjects.
[](https://scaleregenerativehealth.com/bioregulators/vilon)
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- Headaches: Infrequent mild headaches, often transient.
[](https://scaleregenerativehealth.com/bioregulators/vilon)
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- Cancer Treatment Concerns: High doses (100 mg/kg) with cyclophosphan reduced survival in mice with lung carcinoma, suggesting caution in chemotherapy combinations.
[](https://www.peptides.org/vilon-dosage-calculator/)
Vilon is generally well-tolerated with no significant adverse effects in most studies, but high-dose combinations require careful monitoring.
[](https://www.peptides.org/vilon-dosage-calculator/)
Other Relevant Details
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- Research Context: Extensively studied in Russia by scientists like Vladimir Khavinson and Vladimir Anisimov for aging, cancer, and immune function; limited Western data due to language barriers.
[](https://www.peptidesciences.com/vilon-20mg)[](https://world-of-peptides.com/vilon-a-comprehensive-peptide-guide-to-its-uses-benefits-dosage-and-in-depth-insights/)
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- Storage: Lyophilized vials stable at room temperature for 3 weeks; store at -20°C long-term or 2-8°C short-term. Reconstituted solutions stable at 2-8°C for 2-7 days or -20°C with 0.1% HSA/BSA.
[](https://www.uk-peptides.com/vilon-peptide)
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- Cancer Controversy: Effective in preventing tumor growth but showed negative outcomes with platinum-based chemotherapy in one study, limiting its adjuvant potential.
[](https://www.peptidesciences.com/vilon-20mg)[](https://biotechpeptides.com/product/vilon-20mg/)
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- Thymic Focus: Part of Thymalin complex, Vilon specifically targets thymus-mediated immunity, distinguishing it from other bioregulators like Epitalon.
[](https://e-peptide.com/shop-information/peptide-therapy/vilon-20mg-peptide-immunomodulator-with-tissue-regeneration-and-healing-action-detail)
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- Not for Human Consumption: Intended for laboratory or in-vitro research only, per supplier guidelines.
[](https://www.peptidegurus.com/product/vilon-20mg-bioregulator/)